Leukocyte concentration, red cell concentration, plasma for transfusion, and platelet concentration, are some of the blood products, which are obtained from the processing of single donations of blood or plasma. In whole blood, red blood cells, leukocytes, and platelets are suspended within the plasma. Blood plasma is the liquid component of the whole blood, and makes up approximately 55% of the total blood volume. It is a complex biological material mainly composed of water with small amount of minerals, ions, nutrients, salts, and proteins in the solution. Human plasma is composed of protease inhibitors, protease, fibrinolytic proteins, coagulation factors, and anti-coagulant proteins. Human plasma is obtained through large scale processing steps known as fractionation, i.e. a sequence of process in which plasma is separated for medicinal use. Human blood plasma is obtained by separating the plasma from the whole blood or by apheresis.