Dry eye disease is a disorder of the tear film that occurs when the eyes are incapable to produce tears, which are required to maintain lubrication and moisture on the surfaces of the eyes. It is commonly known as dry eye syndrome or dry eye. Major symptoms include irritation, blurred vision, and burning sensation. If left untreated, it leads to pain, ulcers, and loss of some vision. Complete loss of vision is uncommon with the dry eye disease. Alternative medical terms which are used to describe the dry eye disease include keratoconjunctivitis sicca (affects cornea and conjunctiva), keratitis sicca (dryness and inflammation of the cornea), and dysfunctional tear syndrome (inadequate quality of tears). The two types of the disease are aqueous tear-deficient dry eye and evaporative dry eye. In aqueous tear-deficient dry eye, the lacrimal glands fail to produce ample of the aqueous component of tears to uphold a healthy eye surface. Evaporative dry eye may result from inflammation of the meibomian glands. These glands make the lipid part of tears that slow down evaporation and keep the tears stable. Globally, the dry eye disease affects approximately 60 million people. This disorder can affect individuals of any age, but it is most common in elderly people (prevalence of about 5%-30% above the age of 60?years). It affects primarily women as compared to men due to hormonal changes. Use of certain medications such as antihistamines, analgesics, and antidepressants increases the risk of developing the dry eye disease. People with diabetes, rheumatoid arthritis, and thyroid problems are more likely to have symptoms of the disease.