Neuroblastoma (NB) is the most common cancer in childhood and infancy. Neuroblastoma is a cancer that starts in primitive nerve cells. It rarely occurs after age around 10 years. Neuroblastoma is sometimes caused by a gene mutation passed from the parent to the child. It commonly starts in the adrenal glands, it usually grows into a large, firm mass that presses other organs. It can also develop in nerves near the backbone and in the spinal cord, neck, chest, or abdomen. Some of the most common symptoms of the neuroblastoma are firm mass in the abdomen, enlarged stomach, weight, anemia, crankiness, fever, bone pain, bulging eyes, dark circles around the eyes, weakness, and high blood pressure.