The tandem mass spectrometry systems market for 2012 was estimated to be valued at $ 1.3 billion globally with the greatest demand from pharmaceutical industry and preclinical research and is forecast to reach $ 2.3 billion by 2018.
San Mateo, CA -- (SBWIRE) -- 02/05/2014 -- Mass Spectrometry has been applied in life science research for over 40 years. Over these years several technological advancements have evolved to cater specific requirements in various life science areas. The mass spectrometry market had observed an all time low between 2008 and 2010, largely due to economic crisis that took place globally. This has changed as MS has observed a progressive growth due to increasing demand from research facilities, increased government funding in healthcare and life science, increasing demand from developing countries particularly in Asia, Middle East and South America. The increasing demand came particularly as drug discovery and development growth spurt took place since patent expiry of several billion dollar blockbuster API’s were expected to lose patent in the coming few years. Generic companies who were experts in reverse engineering of drugs in India, Brazil and China among a few others increased investment in healthcare research funding which has further fuelled the investment of research facilities in better equipment and tools.
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Tandem mass spectrometry systems utilize the two MS systems where the first round of MS causes precursors to fall apart by various techniques of degradation and the second round of MS separates the fragmented components by weight. There are several tandem MS combinations that are available based on the type of requirements raised by a buyer. The MALDI Triple-TOF, Q-TOF and triple quadrupole are the most utilized types of tandem mass spectrometers in demand today. Tandem MS has been applied to several emerging areas in healthcare and life-science such as Metabolomics for studying Vitamin biochemistry, environmental and food toxicology besides its primary use in proteomics. Some recent rat plasma studies have conducted research on various constituents such as brazilin and pinosylvin in pre-clinical pharmacokinetic studies and buflomedil in human plasma for bioequivalence studies. Q-TOF is expected to compete against FT-MS due to a competitive cost and quality in terms of resolution delivered by both systems.
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