Hialeah Gardens, FL -- (SBWIRE) -- 05/30/2014 -- Simplicef is used to treat animals with skin infections, such as wounds and abscesses caused by the of bacteria susceptible to-lactam antibiotics (Staphylococus intermedius, Staphylococcus aureus, Streptococcus canis, Escherichia coli, Pasteurella multocida and Proteus mirabilis).Simplicef is a brand name drug, but a generic equivalent is available. The generic form, called Cefpodoxime proxetil, can be used in dogs. Although the generic equivalent contains the same active ingredient, it costs less.
Once the surface of the skin is damaged due to some kind of injury, it becomes more susceptible to various bacterial infections. Dogs are dynamic pets prone to injuries during their everyday activities whether they are playing or fighting. Wounds and cuts on the skin can easily become infected. Such wound is inflamed, red and swollen, often with purulent discharge. In some cases, animals can even get feverish and lethargic. Dogs can often develop a bacterial infection of the skin caused by some other pre-existing condition or predisposing factor. The affected areas of the skin are itchy, swollen and crusted, filled with small raised, pus-filled lesions. Partial loss of hair is quite common in such cases.
Skin infections in dogs are often associated with the secondary superficial pyoderma, one of the most common dermatologic conditions in household pets. In dogs, pyoderma is often caused by the Staphylococcus intermedius or Streptoccocus canis.Wounds or abscesses can often lead to skin infections. The damaged surface of the skin provides an entering point for bacteria.Dogs suffering from fungal infections or endocrine diseases (hyperthyroidism) are at higher risk of developing skin infections. Flea bite, food allergies and infestations with external parasites (e.g. Demodex) are also predisposing factors for skin infections.
Relative Info On Breeds Most Associated With This Ailment:
All dogs are susceptible to skin infections, but certain types of dogs are predisposed to developing pyoderma. Breeds with a short coat, skin folds (such as bulldogs, shar pei, sphinx cats) and pressure calluses are likely to suffer from skin infections. Higher incidence of pyoderma has been noted in the population of German shepherd dogs.
How It Works:
Active ingredient of Simplicef is cefpodoxime proxetil, a prodrug that gets activated into cefpodoxime in the gastrointestinal tract. Cefpodoxime is a cephalosporin antibiotic from the group of ?-lactam antimicrobials. It impairs the synthesis of the bacterial cell wall, subsequently killing the bacteria. Cefpodoxime if very effective against both Gram positive and Gram negative bacterial, especially E. coli, Staphylococci, Streptococci, Proteus and Pasteurella infections in dogs.
Directions For Use:
Simplicef tablets are prescribed by a licensed veterinarian and must be used strictly according to veterinary instructions. To ensure better absorption, Simplicef tablets should be administered with food. The product label contains detailed instructions for use.
Dosage And Administration:
The usual dose range of Simplicef is between 5 and 10 mg/kg of body weight or 2.3-4.5 mg/lb of body weight. The tablets are administered by mouth once a day. Although the tablets can be given without food, it is advisable to administer them with a meal to help the absorption of the drug in the body. The treatment with Simplicef tablets usually lasts for 5-7 days or at least 2-3 days beyond the cessation of symptoms, depending on the nature and severity of infection. Simplicef tablets should not be administered longer than 28 days in a row.
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