Unveiling the Future of Tangential Flow Filtration Market: 2023-2028 Global Analysis, Top Stakeholders, and Anticipated Trends

In May 2022, Merck KGaA invested over USD 476.7 million to expand its membrane and filtration manufacturing in Ireland.


Northbrook, IL 60062 -- (SBWire) -- 08/25/2023 --According to a recent report by MarketsandMarkets™, Tangential Flow Filtration Market exhibited significant growth, with estimated revenues of $1.9 billion in 2023. This dynamic market is projected to continue its upward trajectory, reaching a substantial $3.6 billion by 2028, reflecting a remarkable Compound Annual Growth Rate (CAGR) of 13.5% during the period from 2023 to 2028.

the Tangential Flow Filtration Market is on a robust growth trajectory, driven by factors such as its superior performance compared to traditional filtration methods, the adoption of single-use technologies, adherence to industry standards, increased pharmaceutical investments, and the burgeoning biopharmaceutical sector. With a projected CAGR of 13.5% from 2023 to 2028, this market presents substantial opportunities for stakeholders and underscores its vital role in modern bioprocessing and pharmaceutical manufacturing.

The tangential flow filtration (TFF) industry is poised for significant growth and innovation in the near future. With advancements in biotechnology, pharmaceuticals, and bioprocessing, TFF has emerged as a vital technique for separation and purification processes. In the coming years, we can expect to see the development of more efficient TFF systems, improved membranes, and enhanced process monitoring and control capabilities. The industry will likely witness a surge in demand for TFF solutions as the biopharmaceutical sector continues to expand, driven by the rising need for biologics and personalized medicine. Furthermore, the adoption of TFF in other industries, such as food and beverage, water treatment, and chemical processing, is expected to increase, fueling further growth. As TFF becomes increasingly integral to various applications, we can anticipate the emergence of novel TFF technologies, automation, and digitalization to optimize process efficiency, reduce costs, and ensure product quality and safety. Overall, the future of the tangential flow filtration industry appears promising, driven by technological advancements and the growing demand for reliable and scalable separation solutions.

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In 2022, the systems segment accounted for the largest share of the product segment in the Tangential Flow filtration market.

On the basis of products, the tangential flow filtration market is segmented into systems, membrane filters, and other tff products. In 2022, the systems segment accounted for the largest share of the market and is expected to grow at the highest CAGR during 2023-2028. Tangential filtration systems consist of automated and mechanical filtration systems. These systems provide maximum operational reliability. Some of the benefits associated with these systems include a high retention rate, less consumption of energy, low cost, and reduced cross-contamination risk. With the help of such systems, pharmaceutical companies can achieve the highest quality products. The systems segment is further segmented into single-use and reusable systems. Single-use systems are gaining importance in separation and purification applications. Developments in research techniques and increased demand for more specificity in the filtration process are increasing the adoption of single-use technologies in many small-scale biopharmaceutical processes.

In 2022, the microfiltration segment accounted for the largest share of the technique segment in the Tangential Flow filtration market.

On the basis of technique, the tangential flow filtration market is segmented into microfiltration, ultrafiltration, nanofiltration, and other techniques. In 2022, the microfiltration segment accounted for the largest market share. The filters used in this technique can be in a submerged configuration or a pressure vessel configuration; they can be hollow fibers, flat, sheet, tubular, or spiral. Membrane filtration technique can be used for removing suspended matter (>99%), harmful microorganisms (e.g., bacteria, protozoa, algae, and fungi) (>99%), and PAHs. Also, MF can be implemented to break down emulsions. Microfiltration with hollow-fiber filters finds applications in processes such as clarification, purification of cell broths, separation of cell debris, and separation of macromolecules. This technique is also used for harvesting cells in upstream bioprocessing and for the recovery & purification of biomass during the production of antibiotics. In biotechnology, microfiltration is used for the retention of biomass from fermentation broths. This technique is also used for the removal of natural and synthetic organic matter to reduce the fouling potential.
In 2022, the Asia Pacific region is the fastest-growing region of the Tangential Flow filtration market.
The tangential flow filtration market is divided into five regions including, North America, Europe, Asia Pacific, Latin America and Middle East and Africa. The Asia Pacific market is expected to register the highest CAGR during 2023-2028. Factors responsiblr for the growth includes, unique industry dynamics accompanied by a highly competitive landscape owing to its complex and diverse regulatory landscape and varying pharma industry infrastructures across each country, impacting innovation in each country.

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Tangential Flow Filtration Market Dynamics:


1. Growing advantages of tangential flow filtration over normal flow filtration
2. Rising R&D spending in pharmaceutical & biotechnology industries
3. Increasing adoption of single-use technologies
4. Increased adoption of Good Automated Manufacturing Practice (GAMP)


1. High capital investments for new production facilities to limit the entry of small players


1. Emerging economies offer lucrative growth opportunities
2. Rising therapeutic applications of recombinant proteins


1. Increased complexities introduced by the interaction of charged excipients and proteins to restrict the market growth
2. Difficulty in the survival of small players and new entrants

Key Market Players:

Key players in the Market include Merck KGaA (Germany), Danaher Corporation (US), Sartorius AG (Germany), Parker Hannifin Corporation (US), Repligen Corporation (US), Alfa Laval Corporate AB (Sweden), ANDRITZ (Austria), Meissner Filtration Products, Inc. (US), Cole-Parmer Instrument Company, LLC (US), Solaris Biotechnology Srl (Italy), Koch Separation Solutions (US), Sterlitech Corporation US), Synder Filtration, Inc. (US), PendoTECH (US), ARTeSYN Biosolutions (Ireland), Microfilt India Pvt. Ltd. (India), Bionet (Spain), SYSBIOTECH GmbH (Austria), Cobetter Filtration Equipment Co., Ltd. (China), Biotree (India), FORMULATRIX (US), Mantec Technical Ceramics Ltd. (UK), Smartflow Technologies (US), TAMI Industries (France), and SPF Technologies LLC (US).

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Recent Developments:

- In May 2022, Merck KGaA invested over USD 476.7 million to expand its membrane and filtration manufacturing in Ireland.

- In December 2021, Repligen Corporation acquired Bioflex Solutions, which offers single-use fluid management products.

- In June 2021, Repligen Corporation signed an agreement to acquire Polymem, which offers hollow-fiber membranes and modules.

- In March 2021, Pall Corporation acquired Austar Lifesciences Limited. The acquisition aimed to expand the company's capacity to support single-use technology.

Media Relations Contact

Aashish Mehra

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