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All Penny News: Senseco Releases Optimistic Data from Third Cohort in Blood Cancer Clinical Trial

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Mississauga, ON -- (SBWIRE) -- 12/09/2013 -- Media, Inc. ( announces its latest article titled “Senseco Releases Optimistic Data from Third Cohort in Blood Cancer Clinical Trial.”

Companies mentioned in this article include Senesco Technologies, Inc. (OTCQB:SNTI) and Celgene (Nasdaq:CELG).

Article Excerpt:

Lymphona is the most common type of blood cancer, occurring when lymphocytes, a type of white blood cell, multiply and grow uncontrollably. There are two main types of lymphocytes, B-cells and T-cells, which can develop into one of two primary types of lymphoma, Hodgkin and non-Hodgkin, and spread to various parts of the body. The most common form of non-Hodgkin lymphoma (NHL) is diffuse large B-cell lymphoma, accounting for nearly one-third of newly diagnosed NHL cases. In the United States alone, there are about 120,000 cases of diffuse large B-cell lymphoma.

Blood-borne cancers are the focus of Senesco Technologies, Inc. (OTCQB:SNTI) with its flagship therapeutic SNS01-T. The company’s gene regulation technology is comprised of three components: a DNA plasmid, a small inhibitory RNA (siRNA) and polyethylenimine, which cumulatively work to target damaged cancerous cells and destroy them.

Pre-clinical research showed SNS01-T combined with Celgene’s (Nasdaq:CELG) lenalidomide (Revlimid) outperformed lenalidomide alone in mouse models of multiple myeloma. Lenalidomide is a derivative of thalidomide that is commonly used to treat blood cancers. In the study, implanted myeloma tumors were eradicated after a single six-week dose cycle of the combination in 67 percent of the mice, with no regrowth after two months without treatment. All the mice in the study lived 102 days to the conclusion of the trial.

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