Albany, NY -- (SBWIRE) -- 03/13/2015 -- In the healthcare industry, adhesion refers to the formation of scar tissue formed when organs and tissues cling to each other after a surgery. While adhesion is a natural and normal step in the body's healing process, it becomes a severe problem when a cross-connection arises due to adhesion, i.e. when tissues attach to otherwise unrelated tissues.

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Problems Caused by Adhesion

Adhesions can lead to several severe clinical complications such as loss of sensation, infertility, intestinal blockage, and pelvic pain. The nature and magnitude of the symptom depend on the location and size of the adhesion. Most of the aforementioned symptoms are caused due to adhesions formed after surgery in the abdominal region. Post-surgery complications include the adherence of pelvic organs and bowels with each other. Major forms of adhesions are named based on their location, such as:

Pelvic adhesions
Intraperitoneal adhesions
Intestinal adhesions
Abdominal adhesions
Increasing Incidence Leads to Growing Market for Anti-Adhesion Products

The number of patients suffering from post-surgery adhesions is increasing. 55%-90% of patients that undergo gynecological and/or abdominal surgeries face complications related to uncontrolled adhesions.The global anti-adhesion products market is segmented according to the location of surgery, including abdominal surgery, gynecological surgery, and other surgeries. Adhesions are prevalent especially in North America, which is the leading consumer in the global anti-adhesion products market. The Food and Drug Association has approved a number of drugs in the global anti-adhesion products market that are effective in preventing or curing the patient of adhesion complications.

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Key Players and Products in the Global Anti-Adhesion Products Market

Some of the top companies in the global anti-adhesion products market are identified according to the branded product that they sell. The list includes Surgiwrap by MAST Biosurgery, Interceed by Johnson & Johnson, Seprafilm by Genzyme, and Adept by Baxter. Other important companies in the global anti-adhesion products market include LifeCell Corporation, Angiotech Pharmaceuticals, Inc., Anika Therapeutics, Inc., and WL Gore.

Use of Adhesion Barriers

Adhesion barriers are gels, fabrics, or films that are usually applied between tissue layers immediately after a surgery. They ensure that once the incision is closed, the possibilities of adhesion are extremely low. If applied correctly, the barrier becomes a physical shield that keeps the damaged tissue separate from the surrounding healthier tissue. This is done so that the damaged tissue does not adhere to its surrounding tissue layers during the healing process. Adhesion barriers are created in such a way that once the internal wound is healed in 3 to 7 days, the barrier automatically dissolves into bodily fluids, gets absorbed, and is excreted naturally.

For example, Genzyme's Seprafilm is a popular barrier in the global anti-adhesion products market. It is a clear and sticky compound that is made using chemically modified sugars. A few of the chemicals used in Seprafilm are actually naturally present in the human body. Seprafilm sticks to the tissues and is absorbed by the body after seven days. Johnson & Johnson's Interceed is another barrier that is composed of artificial cellulose. The cellulose is knitted into a fabric that swells and slowly gets converted into a gel once it comes into contact with the damaged organ. Baxter's Adept is actually an Icodextrin solution. All three of these adhesion barriers are FDA-approved. Gore-Tex, another leading barrier, is said to be more efficient than Interceed. It, however, requires an additional surgery to be removed.

The global anti-adhesion products market currently does not include any approved drugs that can be used for the prevention or removal of adhesions. Most of the research in this field is carried out on animals. At the same time, the global anti-adhesion products market does include some products that prevent adhesion of tissue to support meshes used for hernia patients. Such developments keep the global anti-adhesion products market in a growth phase, enabling better products to replace conventional ones and ensuring safer surgical recoveries.

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