The C-terminal domain has epoxide hydrolase activity and acts as on epoxides such as oxiranes and alkene oxides; and arene oxides
Albany, NY -- (SBWIRE) -- 06/04/2019 -- The C-terminal domain has epoxide hydrolase activity and acts as on epoxides such as oxiranes and alkene oxides; and arene oxides. Bifunctional epoxide hydrolase 2 plays an instrumenetal role in xenobiotic metabolism through degrading potentially toxic epoxides. In addition, bifunctional epoxide hydrolase 2 also decides steady-state levels of physiological mediators. Meanwhile, the N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9, 10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid. These insights are according to the report titled, "Global Bifunctional Epoxide Hydrolase 2 Market Research Report 2019," which has been lately added to Market Research Hub's (MRH) exhaustive repository. Soluble epoxide hydrolase is a bifunctional enzyme which in humans in encoded by the EPHX2 gene. As such, mammalian soluble epoxide hydrolase converts epoxides to their corresponding diols through the addition of a water molecule. Soluble epoxide hydrolase (sEH) hydrolizes lipid signaling molecules, incorporating the epoxyeicosatrienoic acids (EETs). Owing to central physiological role in disease conditions such as diabetes, hypertrophy, pain sEH, and hypertension are being scrutinized as a therapeutic target. In addition, sEH is perceived to be the hepoxillin hydrolase which is responsible for inactivating the epoxyalcohol metabolites of hepoxilln A3, arachidonic acid and hepoxiin B3.
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Bifunctional Epoxide Hydrolase 2 Market: Report Content
The report offers a robust assessment on the bifunctional epoxide hydrolase 2 market underpinned by quantitative and qualitative analysis. In addition, the report focuses on the dynamics of the market that have significant influence on the development of the Bifunctional epoxide hydrolase 2 market, elucidating drivers, trends, opportunities and restraints. The report focuses on the segmentation of the market to provide a deep dive assessment of the market. The report incorporates executive summary and overview section that presents a robust assessment on the bifunctional epoxide hydrolase 2 market. Moreover, the report in the market overview section sheds light on PESTLE analysis to offer comprehensive analysis on the market. Further, the overview section further throws light on Porters' Five Force analysis which will aid in assessing competitive landscape with respect to bifunctional epoxide hydrolase 2 market. The coherent analysis of competitive scenario of the bifunctional epoxide hydrolase 2 market is backed up by the Porters' Five Force Analysis. Further, the Porters' Five Force Analysis focuses on feasible strategies of the pertinent players in the bifunctional epoxide hydrolase 2 market. Additionally, the report also elucidates SWOT analysis, company profile, product portfolio, recent development, company profile, key differentiation and annual revenue.
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Bifunctional Epoxide Hydrolase 2 Market: Research Methodology
The report is propelled by painstaking research conducted to offer a deep dive analysis. Primary research and secondary research have been applied to offer a judicious insights on bifunctional epoxide hydrolase 2 market. The report is underpinned by primary research, incorporating veracious review from experts, telephonic interview, genuine views from seasoned analyst and surveys. Meanwhile, the secondary research encompasses EC filing, Factiva, trade journals and resourceful database. Additionally, the report shed light on absolute dollar opportunity analysis and Y-o-Y projections.