Recently published research from Espicom Business Intelligence, "Biosimilar Opportunities in an Evolving Market", is now available at Fast Market Research
Boston, MA -- (SBWIRE) -- 09/16/2013 -- Biosimilars: another milestone passed
At the end of June 2013, the European Medicines Agency's Committee for Medical Products for Human Use issued a positive opinion for the first biosimilar version of Johnson & Johnson's infliximab for the treatment of rheumatoid arthritis, inflammatory bowel disease and plaque psoriasis. For the two successful applicants, Celltrion and Hospira, this development passes a significant milestone for the whole biosimilar sector as the products are the first monoclonal antibody (mAb) therapies to reach a positive opinion following review via the EMA biosimilars regulatory pathway. This is an important event which heralds a new era of lower-cost biological therapies in Europe.
For J&J and its partners, the news is less welcome. Already under pressure from branded competitors in the TNF inhibitor market, it is no surprise that both developer and biosimilar companies will be assessing what share they may secure of its US$6.13 billion revenues.
View Full Report Details and Table of Contents
The tip of a US$41 billion iceberg
While significant for J&J, infliximab is just the tip of the iceberg when it comes to the potential for biosimilars. In terms of revenue, six of the top ten pharmaceutical therapies are biological products, which have been targeted by biosimilar developers: Abbvie's Humira (adalimumab), Roche's MabThera (rituximab), Herceptin (trastuzumab) and Avastin (bevacizumab), Sanofi's Lantus (insulin glargine), and Johnson & Johnson's Remicade (infliximab). These products had combined global sales of US$41.4 billion in 2012. Also
of significant importance to biosimilar developers, with sales of US$4.2 billion in 2012 is Amgen's Enbrel (etanercept).
Open season: Branded industry gets in on the act
It may have taken a while, but the world's major pharmaceutical originators have recognised the potential for biosimilars. A number have disclosed their intentions and/or announced clinical trials in recent months. For example, in February 2013, Amgen announced plans to launch a portfolio of six new biosimilars beginning in 2017: adalimumab, infliximab, bevacizumab, trastuzumab, rituximab and cetuximab. Four of these projects form part of the
company's development agreement with Actavis. In June 2012, Merck KGaA and Dr Reddy's Laboratories announced a partnership to co-develop a portfolio of biosimilar compounds in oncology, primarily focused on monoclonal antibodies. Pfizer has been openly active in generics and biosimilars for some time. The company previously had a collaborative deal with Biocon for its insulin products, although this deal was concluded in March 2012. In May 2013, Pfizer began a Phase I trial with an infliximab biosimilar, PF-06438179. Many smaller biosimilar developers have the ambition but not the resources. The increasing interest from big Pharma will bring a welcome boost of expertise and funding to research and partnering.
The US Market: Not the elephant in the room
About Fast Market Research
Fast Market Research is an online aggregator and distributor of market research and business information. Representing the world's top research publishers and analysts, we provide quick and easy access to the best competitive intelligence available. Our unbiased, expert staff will help you find the right research to fit your requirements and your budget. For more information about these or related research reports, please visit our website at http://www.fastmr.com or call us at 1.800.844.8156.
Browse all Pharmaceuticals research reports at Fast Market Research
You may also be interested in these related reports:
- Biosimilars in Developed Countries - Launch of Biosimilar mAbs in Europe and New Regulatory Pathways in the US to Spur Market Growth
- PharmaSphere: Global Biosimilars Strategy - Regulatory Landscape, Key Drivers, Markets and Trends in 2013
- Monoclonal Antibodies Market in Rheumatoid Arthritis to 2018 - Market Characterized by Large and Diversified Pipeline and Low Threat of Biosimilar Sales Erosion
- Latin America Foodservice: Evolving opportunities in a major growth market
- Biobetters in Key Markets - Opportunities for Biotechnology Companies to Sustain Innovation with Low Risk and High Value Offerings
- Global Defense Survey 2013 - Business Outlook, Key Markets and Opportunities
- Global Trends and Consumption Demographics in Soft and Hot Drinks
- Power Markets in Emerging Economies - Market Outlook, Capacity and Generation, Opportunities and Challenges to 2020
- New Consumer Opportunities in Prepared Meals and Meal Components
- Sustainability in the European Construction Industry 2012-2013: Market Trends and Opportunities, Forecast of Budgets and Profitability, Construction Industry Procurement and Marketing Initiatives
Copyright © 2005-2013 - SBWire, The Small Business Newswire - All Rights Reserved - Important Disclaimer
Contact Us: 888-4-SBWIRE (US) - 920-593-5640 (International)