New York, NY -- (SBWIRE) -- 02/16/2018 -- Description:

Epigenetics Market: Epigenetics is a study of heritable changes in gene expression which involves the change in phenotype without changing genotype, which in turn affects the reading of genes by cells. Epigenetic changes are natural and regular processes but also influenced by various factors like lifestyle, environment, age and state of disease. Epigenetic modifications can manifest a common manner of cells which differentiate terminally to end up as liver cells, skin cells, brain cells etc. Epigenetic change may have more damaging effects which can lead to diseases like cancer. Systems like histone modification, non-coding RNA-associated gene silencing and DNA methylation are considered for initiation of epigenetic change sustainably.

Market Outline: Global Epigenetics Market

The surge in the prevalence of cancer, improving funds and aids for the R&D activities, rise in the partnerships between pharmaceutical and biotechnology companies and research institutes, increase in epigenetics application in non-oncology diseases will propel the epigenetics. Moreover, improved advancements in epigenetics technology, untapped potential of emerging markets like India and China are expected to offer many opportunities for the growth of epigenetics market. However, high instrument cost and the dearth of skilled personnel are expected to hamper the growth of the epigenetics market.

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The Epigenetics Market is classified on the basis of enzymes, kits and assays, instruments, application, end user, and geography.

Based on enzymes, the Epigenetics Market is segmented into the following
DNA polymerase
Acetylases
DNA ligases
Methyltransferase
RNA ligases
Reverse Transcriptase
Others

Based on instruments, the epigenetics Market is segmented into the following
Next generation sequencers
Mass spectrometers
Sonicators
qPCRs
Others

Based on application, the epigenetics market is segmented into the following
Oncology
Cardiovascular diseases
Metabolic diseases
Inflammatory diseases
Infectious diseases

Based on kits and assays, the epigenetics Market is segmented into the following
Deep sequencing kit
Bisulfate conversion kit
Methyltransferase assays
Chip- seq kits
Immunoprecipitation kits
Histone assay

Based on end-user, the epigenetics Market is segmented into the following
Pharmaceutical and biotechnological companies
Contract research companies
Academic and Research Institutes

Epigenetics has triggered R&D for new drugs for various cancers, chronic and autoimmune disorders. For example, U.S.FDA approved ramucirumab/Cyramza by Eli Lilly for use in combination with folfiri to treat metastatic colorectal cancer and Novartis's Farydak and Celgene's Istodax received FDA approval in 2015. Introduction of advanced technologies and potential investments on R&D activities are expected to fuel the growth of epigenetics. Currently, companies are focussing on detection of DNA methylation patterns and histone modification. For example, Epigenomic's EPI ProColon 1.0, Quest Diagnostic's ColoVantage, Abbott's Real Time mS9 are few tests which detect SepT9 DNA methylation biomarker for colorectal carcinoma. Development of high specific antibodies for accurate and rapid detection of modifications of histone core proteins. For example, Abcam developed a multiplex assay kit for the detection of various core histone protein modifications.

Geographically Epigenetics Market is segmented as Latin America, Europe, Asia- Pacific, North America, The Middle East & Africa. North America is expected to account for the largest market share in the regional market of epigenetics due to rise in prevalence of cancer, high funding on R&D, increasing acquisitions and collaborations among large pharma companies, high adaptation and awareness of new technologies and healthcare infrastructure. Asia Pacific is a lucrative market owing to the presence of favourable regulatory framework, high incidence and prevalence of diabetes, cancer and cardiovascular diseases among the population of Asia Pacific countries. Mexico, Brazil, and South Africa are expected to show significant growth due to rising economy, a high prevalence of diseases and presence of high unmet needs.

Some of the players in epigenetics market Illumina, Inc. (U.S.), Abcam plc. (U.K), QIAGEN N.V. (Netherland), New England Biolabs, Inc. (U.S.), Merck & Co. (U.S.), Sigma-Aldrich Corporation (U.S.), Genedata AG(Switzerland), Cayman chemical company (U.S), Active Motif (U.S.), Thermo Fisher Scientific, Inc., (U.S.), Diagenode, Inc. (Belgium), Zymo Research Corporation (U.S.). and Episona Inc. (U.S).

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Table Of Contents – Major Key Points

1. Executive Summary

2. Global Epigenetics Market Introduction
2.1. Global Epigenetics Market – Taxonomy
2.2. Global Epigenetics Market –Definitions
2.2.1. Enzyme
2.2.2. Instruments
2.2.3. Application
2.2.4. Kits
2.2.5. End-User

3. Global Epigenetics Market Dynamics
3.1. Drivers
3.2. Restraints
3.3. Opportunities/Unmet Needs of the Market
3.4. Trends
3.5. Global Epigenetics Market Dynamics – Factors Impact Analysis
3.6. Global Epigenetics Market – Regulations
3.6.1. U.S.
3.6.2. Europe

4. Global Epigenetics Market Analysis, 2012 - 2016 and Forecast, 2017 – 2023
4.1. Market Analysis, 2012 – 2016 and Forecast, 2017 – 2023 (Revenue, USD Mn)
4.2. Year-over-Year (Y-o-Y) Growth Analysis (%)
4.3. Market Oppurtunity Analysis

5. Global Epigenetics Market , By Enzyme, 2012 - 2016 and Forecast, 2017 - 2023
5.1. DNA polymerase
5.1.1. Market Analysis, 2012 – 2016 and Forecast, 2017 – 2023 (Revenue, USD Mn)
5.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.1.3. Market Opportunity Analysis
5.2. Acetylases
5.2.1. Market Analysis, 2012 – 2016 and Forecast, 2017 – 2023 (Revenue, USD Mn)
5.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.2.3. Market Opportunity Analysis
5.3. DNA ligases
5.3.1. Market Analysis, 2012 – 2016 and Forecast, 2017 – 2023 (Revenue, USD Mn)
5.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.3.3. Market Opportunity Analysis
5.4. Methyltransferase
5.4.1. Market Analysis, 2012 – 2016 and Forecast, 2017 – 2023 (Revenue, USD Mn)
5.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.4.3. Market Opportunity Analysis
5.5. RNA ligases
5.5.1. Market Analysis, 2012 – 2016 and Forecast, 2017 – 2023 (Revenue, USD Mn)
5.5.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.5.3. Market Opportunity Analysis

Continue……

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