Albany, NY -- (SBWIRE) -- 07/27/2015 -- GPCRs are a large group of cell surface receptors that have an important role in pharmacology in present times. GPCRs or G-protein-coupled receptors have wide-ranging functions in the human body. GPCRs comprise cell surface receptors that respond to an extensive assortment of external stimuli and have a crucial purpose in cell communication. GPCRs are the target for almost 30% of drugs that are on the market as well as the drugs that are presently being developed.

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The GPCRs market is anticipated to expand at an encouraging CAGR of 8.8% to reach a total value of US$3,533.4 million by 2022. The key causes for growth of the global GPCRs market are the mounting demand for a variety of GPCRs assays related to drug development and the proliferation of respiratory, cardiovascular, nervous system, and reproductive disorders all over the world.

HPS and Drug Discovery Platforms Need Drives Demand for cAMP Assay

The category segmentation for GPCRs market is based on six assay types. These are GTP?S binding assays, cAMP assays, receptor internalization assays, reporter gene assays, GTP?S binding assays, and calcium level detection assays. Increasing demand for cAMP assays used in major drug discovery platforms and high throughput screening (HTS) has led to this segment occupying the largest GPCRs market share of 32.5% in 2013. cAMP assays are also used in a variety of drug discovery platforms and range of therapeutic applications, so market growth for this segment can be attributed to demand from these related applications as well. The growth of this segment is expected to continue over the next few years. The cAMP segment was followed by the segment for calcium level detection assays with the second highest market share of the GPCRs market in 2013.

Precision as well as linearity, large signal to background ratio, and wide sensitivity offered by such assays are among the growth factors for assay systems. The reporter gene assay segment is also expected to record significant growth during the coming years.

Oncology Segment Leads Demand from GPCRs Market due to Prevalence of Cancer

The global GPCRs market has seven categories based on therapeutic area. These include the central nervous system (CNS), the cardiovascular system, the immune system, the reproductive system, the respiratory system, oncology, and others (urinary, orthopedics, abdominal). Among these segments, oncology occupied the largest market share in terms of revenue in the global GPCRs market in 2013. Oncology is inclusive of numerous cancer therapy areas such as lung cancer, prostate cancer, leukemia, cervical cancer, and numerous other malignant tumors. The oncology segment is expected to grow substantially over the next few years in the GPCRS market owing to the high occurrence of several types of cancers.

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Among the segments based on geographical regions, North America accounts for the largest market share of the GPCRS market, due to high awareness about advanced assays, financial ability of consumers to buy innovative products, and high investment in healthcare development. The North American GPCRS market is expected to continue growing due to demand for therapeutics against obesity-related illnesses and the growing geriatric population, which is more susceptible to chronic diseases.

The major players in the GPCRs market are Becton, Thermo Fisher Scientific, Promega Corporation, Enzo Life Sciences, Inc., and Sigma-Aldrich Corporation.

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