Albany, NY -- (SBWIRE) -- 07/10/2018 -- This report studies the global Monoclonal Mouse Antibody market size, industry status and forecast, competition landscape and growth opportunity. This research report categorizes the global Monoclonal Mouse Antibody market by companies, region, type and end-use industry.
Monoclonal Antibodies (IgMs) are antibodies that are made by identical immune cells, cloned from a single parent cell. They are therefore of constant structure and bind to the same foreign markers (called antigens). The technology behind the generation of monoclonal antibodies was discovered in 1972 by Csar Milstein and Georges Khler scientists at the Roche-funded Basel Institute for Immunology who were later to win the Nobel Prize. Monoclonal antibodies revolutionized biological research and built the basis for the use of therapeutic antibodies in medicine and for the entire biotechnology industry.
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For antibody discovery, mice are one of the most important sources. They produce similar antibody isotypes with human, including IgA, IgD, IgE, IgG and IgM. Compared with the subclasses of human antibody isotypes, mice contain only one IgA class and the IgG subclasses are known as IgG1, IgG2a, IgG2b and IgG3. In addition, laboratory mice can induce a good immune response to a great range of antigens, even those highly homological human proteins. Moreover, some treatments that unacceptable for humans can also be aboveboard applied for mice with results which are analogous to that from humans. Therefore, the development of mouse monoclonal antibodies is a common choice for a variety of therapeutics and pathology researches. Up to now, the rapid development of therapeutic antibody in the pharmaceutical industry has enabled the mice to play an important role in both monoclonal antibodies discovery and the pre-clinical assessment.
The key players are Roche, Johnson & Johnson, Merck, Novartis, AbbVie, Amgen, Pfizer, Bayer, Lilly, Bristol-Myers Squibb, GlaxoSmithKline, Biogen, AstraZeneca, Sanofi, Alexion Pharmaceuticals, Seattle Genetics and so on.
The leading companies own the advantages on better performance, more abundant products types, better technical and impeccable after-sales service. Consequently, they take the majority of the market share of high-end market. Looking to the future years, the slow downward price trend in recent years will maintain. As competition intensifies, prices gap between different brands will go narrowing. Similarly, there will be fluctuation in gross margin.
Market segment by Type, the product can be split into
- IgM
- IgG
- IgA
- Other
Market segment by Application, split into
- Therapeutic
- Research
- Diagnostic
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Key Stakeholders
- Monoclonal Mouse Antibody Manufacturers
- Monoclonal Mouse Antibody Distributors/Traders/Wholesalers
- Monoclonal Mouse Antibody Subcomponent Manufacturers
- Industry Association
- Downstream Vendors
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