Center for the Biology of Chronic Disease (CBCD)

HPV May Cause Giant Anal Warts; CBCD Reviews the Medical Evidence

HPV can cause a large cauliflower-like mass with an irregular warty surface localized in the anal region. (1)


Rochester, NY -- (SBWIRE) -- 10/30/2015 -- "Infected with the human papillomavirus (HPV)? The CBCD recommends talking to your doctor about a study, which was published in the peer reviewed medical journal, Pharmacology & Pharmacy, and which discusses natural, antiviral remedies against HPV infections." - Greg Bennett, CBCD

The human papillomavirus (HPV) can, in some cases, cause extremely large anal warts. As Dr. Guttadauro and colleagues wrote in a study, "perianal giant condyloma acuminatum is a ... condition related to human papillomavirus infection and characterized by a ... cauliflower-like mass with an irregular warty surface localized in the anal region." (1) Dr. Guttadauro is from the Università degli Studi Milano-Bicocca in Milan, Italy. Dr. Jennifer Lowney wrote that anal warts "are a condition that affects the area around and inside the anus. They may also affect the skin of the genital area. They first appear as tiny spots or growths, perhaps as small as the head of a pin, and may grow quite large and cover the entire anal area. Usually, they do not cause pain or discomfort to afflicted individuals and patients may be unaware that the warts are present. Some patients will experience symptoms, such as itching, bleeding, mucus discharge and/or a feeling of a lump or mass in the anal area." (2) Dr. Lowney stressed that HPV, which causes anal warts is "considered a sexually transmitted disease (STD) … (but) … you do not have to have anal intercourse to develop anal warts." (2)

Click to learn more about HPV symptoms.

How can you be sure that you have anal warts?

"Diagnosis is made by the doctor, who inspects skin around the anus and checks the anal canal with an anoscope (a short instrument inserted into the anus)." (2)

Are there treatments available against the HPV, which causes anal warts?

"There are no drugs approved against the HPV. Current treatments include procedures, such as cryotherapy, conization, and the Loop Electrosurgical Excision Procedure (LEEP). These procedures use liquid nitrogen, a surgical knife (scalpel), a carbon dioxide (CO2) laser, or electrical current to remove the abnormal growths caused by the HPV. These growths include cells that harbor the active virus. The procedures do not target cells with the latent virus. Since they do not remove the latent virus, these procedures only produce a temporary remission." (3) In contrast, the study published in the medical journal Pharmacology & Pharmacy, discusses the formula of a natural antiviral that was shown to reduce HPV symptoms.

"We recommend that individuals infected with the HPV virus download the study and bring it to their doctors." - Greg Bennett, CBCD

Individuals can download the study in .pdf format, here:


(1) Guttadauro A1, Chiarelli M, Macchini D, Frassani S, Maternini M, Bertolini A, Gabrielli F. "Circumferential anal giant condyloma acuminatum: a new surgical approach." Dis Colon Rectum. 2015 Apr;58(4):e49-52.

(2) Jennifer Lowney, MD, FASCRS "Anal Warts" American Society of Colon and Rectal Surgeons (ASCRS)

(3) Polansky H, Itzkovitz E. Gene-Eden-VIR Is Antiviral: Results of a Post Marketing Clinical Study. Pharmacology & Pharmacy, 2013, 4, 1-8