Boston, MA -- (SBWIRE) -- 01/14/2014 -- Although the past decade has seen the atopic dermatitis market remain relatively unchanged and a saturated, highly genericized arena, the coming decade could see the launch of the first biologic, which will set a precedent and pave the way for others to follow suit.
Meda's Elidel contains the molecule pimecrolimus and akin to Astellas' Protopic belongs to the ascomycin class of macrolactam immunosuppressives. The exact mechanism by which Elidel exerts its effect in atopic dermatitis is still unknown (Elidel prescribing information, 2011). However, studies have found that Elidel binds with high affinity to macrophilin-12 (also referred to as 12 kDa FK506-binding protein or FKBP-12) and inhibits the calcium-dependent protein phosphatase, calcineurin. Calcineurin in turn inhibits T cell activation by blocking the transcription of early cytokines.
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- Overview of Atopic Dermatitis, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
- Detailed information on Elidel including product description, safety and efficacy profiles as well as a SWOT analysis.
- Sales forecast for Elidel for the top nine countries from 2012 to 2022.
- Sales information covered for the US, France, Germany, Italy, Spain, the UK, Japan, India and China.
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- Make more informed business decisions from insightful and in-depth analysis of Elidel performance
- Obtain sales forecast for Elidel from 2012-2022 in top nine countries (the US, France, Germany, Italy, Spain, the UK, Japan, India and China)
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