Scottsdale, AZ -- (SBWIRE) -- 03/30/2016 -- Recent developments have shown that there are a lot of off-label prescription scandal when it comes to the use of Zofran during the time of pregnancy by expectant mothers. Manufactured by the Glaxo Smith Kline (GSK), it is an antiemetic medication.

Currently, it has been rated as one of the highest selling drugs. The statistics has been made in the US market alone and does not include markets in the other countries. The record of the medicine shows very clearly that it was originally approved in the year 1991 by the Food and Drugs Administration (FDA). Originally produced to prevent or suppress vomiting and nausea which are consequent to surgical interventions and other cancer related treatment, this 5- HT3 antagonist has recently been used popularly as an off label medication which will treat morning sickness among pregnant women. The bold move actually came with its own risks and the pharmaceutical industry was well aware of it. Recently, a reliable web site called medsnews has gone public with the different kinds of risks, which are associated with the usage of Zofran by pregnant women. The drug works on the mechanism of effectively controlling nausea by suppressing the processing of serotonin. This is a neurotransmitter in the body, which is responsible for initiating the vomiting reflex in the brain. Cases collected in the past couple of years by the web site have indicated that it has caused a severe form of NVP in women, which could potentially harm their health in the long run.

The NVP is also called Hyperemesis Gravidarum. Some of the common symptoms recorded so far are malnourishment, dehydration, electrolyte imbalance and ketoacidosis. The web site has also gathered information on the recall issued by the FDA in the year 2012. The issue recalled 32 mg injectable dose (IV). It has been known to increase the risks related to irregular heart rhythm.

http://medsnews.com/health/zofran-during-pregnancy-the-off-label-prescriptions-scandal/

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