Albany, NY -- (SBWIRE) -- 05/24/2018 -- Molecular cytogenetics refers to the study of chromosomal structures with use of molecular techniques. The technique provides a combination of both molecular and cytological approach to research and diagnosis. Molecular cytogenetics is being considered as an indispensable tool for the diagnosis and research of numerous chromosomal aberrations. The technique is preferred over traditional chromosomal banding technique as traditional techniques provide low resolution level and may escape detection of copy number variations.
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The breakthrough in the molecular cytogenetics technologies such FISH and aCGH are providing new dimensions to the areas of research and molecular diagnostics. These techniques are considered as invaluable tool for gene mapping, gene discovery and complex disease trait analysis. Molecular cytogenetics facilitates diagnosis and prognosis of diseases associated with hematological malignancies and solid tumors at molecular level. Likewise, alongwith diagnosis and prognosis of tumors, the technique is facilitating the practice of personalized medicines. The global molecular cytogenetics market was valued at USD 469.2 million in 2012 and is expected to grow at a CAGR of 23.4% from 2013 to 2019 to reach at an estimated value of USD 1.9 billion in 2019.
Currently, aCGH technique is gaining momentum as compared to FISH technique owing to higher resolution over other traditional banding techniques. Earlier, where cytogenetics field was limited to identification of chromosome structure, it has now expanded its horizons to assessment of structural and functional genetic anomalies. FISH characterized by its ability to interpret information at genome level currently, captures the lion's share of the molecular cytogenetics market. The technique has been utilized over the past decade for identification of various diseases and in suggesting accurate treatment options to the physicians. The technique is known for its accuracy, speed, sensitivity and high resolution over the traditional methods. Further, owing to its growing importance in laboratories the technique is backed by technological advancements such as improved fluroscence microscopes and digital imaging. Moreover, the technique is also supported by ongoing developments in the field of genomics and bioinformatics. FISH has become an essential tool for the validation of diseases and is being extensively used in laboratories and hospitals.
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aCGH technique is rapidly growing with a CAGR of more than 20% and is poised to lead the market in the future. aCGH technique is a high resolution tool and its uniqueness lies in performing thousands of experiments in one array. aCGH has facilitated clinicians to move from sequential diagnostics to parallel diagnostics which provides accurate analysis at one time. aCGH technique is gradually evolving and is expected to surpass FISH technique in the coming years owing to its accuracy and rapid results. aCGH in the next few years would become the primary screening tool while FISH is expected to become more of a validation tool. Moreover, the technology is highly being preferred over FISH owing to its ability to detect several genomes simultaneously. As aCGH provides high resolution copy number variations the technology has numerous application areas in medicine.
Geographically, North America accounts for the largest market for molecular cytogenetics followed by Europe. Growth in these countries is driven by host of factors such as increased level of public awareness, coupled with a large pool of research laboratories. Moreover, growth in the market is also increasing due to rise in cancer incidences and development of personalized medicines. Asia-Pacific is likely to emerge as the fastest growing market during the analysis period. The market in this region is influenced owing to expanding population base, and rising public awareness. Similarly, culture of consanguineous marriage which increases the chances of inheritance of genetic disorders is accelerating the market growth. Suppliers can therefore look forward to the opportunities for molecular cytogenetics techniques in these emerging nations.
Key players in the molecular cytogenetics market include Abbott Laboratories, Applied Spectral Imaging, Affymetrix, Inc., Agilent Technologies, Inc., Illumina, Inc., Life Technologies Corporation, among others.
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