Rockville, MD -- (SBWIRE) -- 12/20/2018 -- Common contaminants in the biopharmaceutical industry, mycoplasmas go undetected without causing any visible changes in cell cultures. Detection of mycoplasma DNA through conventional methods is time-consuming and labor intensive. To resolve the difficulty of detecting mycoplasma macroscopically, cell culturists and microbiologists have been continuously putting efforts to develop most sensitive methods with regard to assay for mycoplasma detection in cell cultures.

The requirement for efficient and accurate mycoplasma detection systems has led the exploration of biochemical assays that rely on differences in the metabolic pathways between host cells, mycoplasma, non-specific staining of the cytoplasmic DNA in mycoplasma-contaminated cells, and PCR-based assays for mycoplasma detection. Research institutes such as the Coriell Cell Repositories (CCR) have adopted polymerase chain reaction method as mycoplasma detection systems.

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Investment Proliferation in R&D to Augur Well for Mycoplasma Detection Systems Development

Investments in R&D activities have significantly contributed to revenue generation in the mycoplasma detection systems market, in parallel to rising healthcare expenditure levels, and research efforts in life sciences industry. Pharmaceutical and biotechnology industries have been conducting rapid research activities, which has been resulting in adoption of novel technologies for drug development and discovery. Mycoplasma detection systems play a vital role in these research activities, and therefore have witnessed great demand in recent years.

Global R&D Funding Forecast states that a rise of 3.5% in R&D investments has been observed worldwide over the past couple of years, with biotechnology, microbiological, and pharmaceuticals researches being of the imperative areas. Funding from governmental bodies to researches related to drug discovery and development, coupled with government initiatives on awareness campaigns apropos of chronic diseases, have been encouraging research-based activities. Additionally biotech companies have been investing heavily for development of more effective mycoplasma detection systems. Such massive amount of R&D expenditure will continue to be a key development determinant for mycoplasma detection systems in the upcoming years.

Development in New Class Therapeutics to Augment Demand for Mycoplasma Detection Systems

Surging popularity of new class therapeutics, which include gene therapy and cell therapy, as a novel treatment approach for several acute and chronic ailments, has further led research institutes and pharmaceutical companies to concentrate more on R&D of these products. As cell therapy involves disassociation of cells from patients and developing cell culture in exterior of the human body, they witness several challenges in their manufacturing. Some key issues include sterilization challenges of products and storage problems, which has led to immediate injection into patients.

Contamination of mycoplasma species such as mycoplasma fermentans, mycoplasma bovis, and mycoplasma arginine in manufacturing process impacts the product quality, reduces production yield, and lowers the expression level. Demand for mycoplasma detection systems grows on requirement for ridding side effects of contamination in humans. Rapid mycoplasma detection systems are now commercially available, which can be utilized in biopharmaceutical manufacturing companies and research laboratories for the purpose of cell-line qualification as well as in-process manufacturing.

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Mycoplasma Detection Systems Market: Clinical Trials Outsourcing to CROs to Create New Avenues for Growth

Biotechnology companies and contract research organizations (CROs) are extensively focusing on mergers & acquisitions activities, and engaging in strategic partnerships, for making developments and advancements in mycoplasma detection systems. Even though clinical researches have been conducted by biotechnological and pharmaceutical companies, outsourcing clinical trials to CROs to comply with requirement for complex safety protocols, dynamic changes in trial demographics, and imposition of stringent regulations by the government has become a new normal among these companies.

Splintered nature of the market for mycoplasma detection systems is a result of the occupancy of several regional as well as international vendors worldwide. This has further intensified competition among players in the mycoplasma detection systems market.

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