Albany, NY -- (SBWIRE) -- 04/17/2018 -- Opioids are strong analgesics that are highly addictive in nature. These are narcotic medications, which are to be administered cautiously to prevent serious side effects. Opioids are recommended for severe pain, which is not expected to be relieved effectively by normal analgesics. The opioid class of painkillers includes codeine, fentanyl, hydrocodone, hydromorphonw, methadone, meperidine, morphine and oxycodone. These opioids are available as single drug product as well as in combination with other analgesic such as oxycodone in combination with acetiaminophen. As these drugs attach to specific proteins called opioid receptors present in brain, spinal cord, gastrointestinal tract and other parts of the body, it can negatively affect these organs if taken for a longer term.
Opioids can cause various side effects such as nausea, constipation, interruption in the CNS functions, prutitis, hyperalgesia, seizures, hallucination and respiratory depression. Long-term use or abuse of opioids can depress respiration and may lead to death if continued. Certain identified opioid induced side effects treatment options to minimize adverse events include dose reduction, symptomatic management and opioid rotation. Physicians support the clinical use of opioid rotation in which, one opioid is exchanged for the other to improve pain control or manage the adverse effects. Symptomatic management includes administration of drugs providing relief from the various side effects.
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Opioid Induced Side Effects Treatment Market: Segmentation
The Opioid Induced Side Effects Treatment Market is categorized based on the side effects caused by opioids and the medications used to treat or reduce the intensity of those side effects. Therefore, based on the side effects, the global opioid induced side effects treatment market is segmented as medications for nausea, constipation, CNS adverse effects and pruritis. Medications for treating opioid induced nausea include antihistamines, antipsychotics and related agents, prokinetic agents and serotonin antagonists.
Medications for opioid induced constipation include methylcellulose, polycarbophil, psyllium, lactulose, polyethylene glycol, sorbitol, magnesium citrate, bisacodyl, docusate sodium and senna. Medications for opioid induced CNS adverse effects include haloperidol, risperidone, dextroamphetamine and methylphenidate. Medications for opioid induced pruritis include antihistamines such as cetrizine, diphenhydramine, fexofenadine, hydroxyzine and loratadine. Some of the other recommended treatment drugs include buprenorphine and naloxone.
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Rising drug abuse and further research development in this field leading to introduction of new products would drive the global opioid induced side effects treatment market. In April 2014, the FDA approved naloxone (Evzio) as an autoinjector dosage form for home use by family members or caregivers.
Some of the key players in the global opioid induced side effects treatment market include AstraZeneca plc, S.L.A. Pharma AG, Shionogi & Co., Ltd., Cubist Pharmaceuticals, Inc., Progenics Pharmaceuticals, Inc., and AIKO Biotechnology, Inc.
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