Pain Therapies Market Players Exhibit Keen Interest in Chronic Neuropathic Pain Treatment, Heralding New Deal Landscape

Pain is an unpleasant sensation or a feeling that is triggered in the nervous system of the human body. It can be sharp or a moderate feeling that can come and go or stay constant; nonetheless it is the primary reason for a consultation and can help in diagnosing the condition.


Albany, NY -- (SBWIRE) -- 09/03/2015 -- Market Research Reports Search Engine (MRRSE), announces the addition of a new report titled 'Frontier Pharma: Pain - Identifying and Commercializing First-in-Class Innovation' to its database. The report, published by GBI research, offers a brief introduction to pain and its various subtypes before offering a lowdown on the treatment algorithms and pharmacotherapy for the indication. Besides other important facets of the pain market, the report also discusses how the molecular target landscape has witnessed a change. The most important aspects of innovation have been investigated further to help analysts emerge with specific details about the stage of development of these therapies, the molecular target and molecule type.

The deal and co-development landscape of the pain therapies market has been meticulously assessed; critical changes in the licensing environment are also reviewed.

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According to the findings of the report, the active pain pipeline is composed of as many as 796 products at all development stages. This gives evidence of the highly diverse array of molecular targets that are present in the active pain pipeline. The report identifies 122 first-in-class active-stage development programs. These programs account for about 13.6% of the entire pipeline, demonstrating the high degree of innovation that exists within the active pain pipeline.

The pain therapeutics market, on the other hand, presents a divergent picture. A paltry rate of innovation has been reported from the pain therapeutics market over the last decade because of the continued dominance of traditional active pharmaceutical ingredients.

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Opioids dominate the segment for moderate-to-severe pain. But their potential for abuse has prompted pharmacos to reformulate opioids into abuse-resistant version. In the mild pain treatment segment, non-steroidal anti-inflammatory drugs (NSAID) enjoy a leading position. However, these drugs do not provide adequate treatment for certain types of chronic pain and neuropathic subtypes.

While most first-in-class innovation programs in the active pain pipeline still fall within the limits of early-stage development, the majority of these programs are centered on novel molecular targets for neuropathic pain – the most incapacitating and complex variety of chronic pain. Market players focusing on these drug classes could possibly alter the course of the pain therapies market.

The pain deals ecosystem has been abuzz with several licensing and development agreements being signed over the last decade. The report finds that during this period, 112 co-development and 261 licensing agreements were signed. Despite investment dollars being channeled into the pain therapies market, there has been a conspicuous lack of deals and agreements for first-in-class products. Going forward, the unmet need for therapies to treat chronic pain and breakthroughs in research related to pathophysiologies of pain-subtypes will help foster more licensing and co-development partnerships.

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