Pennsylvania Reproductive Specialists

Discovery May Lead Directly to Increased IVF Success at Pennsylvania Reproductive Specialists


Chalfont, PA -- (SBWIRE) -- 03/16/2015 -- A recent study reveals that researchers have discovered a possible cause of in vitro fertilization implantation failure. The study, published in the Journal of Cell Science, was conducted by scientists at the University of Manchester's Institute of Human Development. According to the study, it possible that microRNA molecule levels can affect the implantation rate of embryos during IVF procedures. Study results like these may directly lead to improved technology and increased success rates at Pennsylvania Reproductive Specialists, an IVF clinic near Philadelphia.

Such news is worth celebrating to patients in the care of Dr. Annette Lee of Pennsylvania Reproductive Specialists. Pennsylvania Reproductive Specialists is already one of the most successful fertility clinics in the Philadelphia area, with a 74% rate of pregnancy per IVF treatment in patients under age 35, well above the worldwide average of 32% put forth in the study. However, the clinic is determined to continue to increase its success rate and end infertility woes for its patients.

In-vitro fertilization is a delicate process. First, eggs and sperm cells are collected in minimally invasive procedures, and then combined in a laboratory environment conducive to fertilization. Once the eggs have been fertilized, the embryos are gently transferred to the uterus. While Pennsylvania Reproductive Specialists have a high rate of success, IVF is not yet a perfect process, and frustrating failures still occur. However, The University of Manchester study sheds new light on the process, resulting in information that may later be used to improve IVF technology.

The study suggests that the molecule called microRNA, or miRNA, inhibits another molecule called insulin-like growth factor receptor 1, or IGFR1. According to Professor John Aplin, who co-wrote the study, it is possible that IGFR1 must be present in order for the embryo to successfully implant in the uterus. Previously, this was completely unknown information.

Discoveries like this one are a boon to Pennsylvania Reproductive Specialists and its patients. An increasingly comprehensive understanding of the implantation process and its deterrents can lead to new fertility technology in the future, which may later be utilized by the experienced fertility doctors at the Philadelphia area clinic.

For more information on in vitro fertilization and other fertility treatments and care, call 215-822-8400 or visit

About Pennsylvania Reproductive Specialists
Dr. Annette Lee, M.D., the physician at Pennsylvania Reproductive Specialists, is double board-certified in OB/GYN and Reproductive Endocrinology. After over a decade perfecting her clinical skills in some of the largest and most successful IVF centers in the US, she established PRS in 2009 with the goal of offering the same cutting edge care in a very patient-friendly environment. awarded Dr. Lee the "Patient's Choice" award in 2010, 2011, 2012 and 2013 based on exemplary patient reviews and rating. Dr. Lee was named by Castle Connolly as a "Top Regional Doctor" in 2014 and also named as one of's Top 10 Reproductive Endocrinologists.

For more information call 215-822-8400 or visit