Transparency Market Research

Single Nucleotide Polymorphism (SNP) Genotyping: Key to Early Disease Diagnostics

Transparency Market Research Report Added "SNP Genotyping and Analysis Market" to its database.


Albany, NY -- (SBWIRE) -- 09/02/2016 -- Single nucleotide polymorphism (SNP) analysis is used as a research tool to identify genomic variations that lead to different,commercially important morphological traits and can determine the health and ancestry of plants and animals.SNP genotyping commands a significant share of the total genotyping market and is a key research tool in the field of genomics. According to a recent report published by a leading market research firm Transparency Market Research, the global market for SNP genotyping and analysis was valued at USD 2,385.2 million in 2012 and is expected to grow at a CAGR of 21.8% from 2013 to 2019, to reach a value of USD 9,485.2 million in 2019.

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High throughput multiplex genotyping began with the introduction of the first DNA sequencing technologies such as Maxam-Gilbert sequencing of nucleotides, shotgun sequencing, and Sanger sequencing followed finally by third generation sequencing platforms such as Solexa, 454 pyrosequencing and others, through a period of almost half a century. During this time, several research projects were initiated, of which, the most successful held by far is the Human Genome Project. The sequencing cost for the project was billions of dollars and a need for faster, robust and reliable systems was realized.

During this time, several other applications within genetics and genome studies began as the first SNPs were identified after restriction fragment length polymorphism (RFLPs) and microsatellites. The rise of commercialization in plants and animals to feed a burgeoning population of the world and a requirement for assuring unhindered quality in these products year after year ended in research of studying genotypic and phenotypic traits more closely after Mendel's studies. These traits were held responsible due to the RFLPs and other genomic variations, and finally SNPs or "snips" were concluded to be the obvious factors for variations.

The Taqman AD is used in case of a small number of SNPs and large populations. Major drivers for the technology are simple usage design, high efficacy and conversion rate, and applications in agriculture and animal breeding for the bovine and porcine markets toimprovethe quality of meat and dairy products, prevention of diseases caused by micro flora such as Campylobacter jejuni, which causes diseases in cattle, poultry and humans. Illumina's Animal GeneChip platforms such as Bovine Chip and Equine Chip are in popular demand for determining breed quality and disease-prone livestock.

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Falling prices in sequencing will drive research and development in SNP genotyping along with demand from the agricultural and animal husbandry segments. Increasing consumption of meat over the world is contributing greatly to the need for introducing improved methods of identifying disease-prone and high-risk meat animals. Awareness of genetic diseases and demand for methods to identify high risk cases in early childhood or the fetal stage by SNP genotyping can reduce the number of cases over the world, which in turn will reduce the trauma for families as well.

Key players in the global market are Life Technologies Corporation, Illumina Inc, Affymetrix, Sequenom, Fluidigm and Roche with others such as Agilent Technologies, Millipore, Qiagen, WaferGen and ThermoFisher Scientific. ThermoFisher Scientific is expected to benefit greatly from its acquisition of Life Technologies and will become a leader in several segments including SNP Genotyping through its USD 14 billion acquisition in 2013.

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