YMC America, Inc.

YMC America Describes Separation of mAb by Size Exclusion

 

Allentown, PA -- (SBWIRE) -- 09/14/2020 -- YMC America describes a size exclusion chromatography column in a 2-page brochure. The column is optimized for aggregates and fragments of monoclonal antibodies (mAb).

YMC-SEC MAB utilizes a dihydroxypropyl stationary phase bonded to a silica gel base. The particle size is 3 µm, and the pore size is 250Å.

Because of the particle size and pore size of the column, YMC-SEC MAB is able to separate aggregates from the mAb monomer and also resolve lower molecular weight mAb fragments.

YMC-SEC MAB is useful across a wide molecular weight range, from 10kDa to 700kDa, to be exact.

YMC-SEC MAB is recommended for SEC analysis of antibody-drug conjugates using organic-containing mobile phases.

The columns characteristically show high reproducibility lot-to-lot and long useful lifetime. They are ideal for both research and quality control applications.

A column durability test displayed in the flyer illustrates no meaningful performance degradation after more than 500 injections (monoclonal antibody analysis).

The flyer also documents the lot-to-lot reproducibility of the columns and shows separations of humanized monoclonal antibody (mAb) and antibody-drug conjugate (ADC).

Read more about YMC-SEC MAB here.

Contact YMC America by email at info@ymcamerica.com or call their direct line at 888-341-8380 to obtain a copy of the YMC-SEC MAB flyer or to buy columns.

About YMC America, Inc.
Established in 1980, YMC America, Inc. is worldwide full-service liquid chromatography company, which offers sales, technical product support, service, application assistance, purification services, contract synthesis and method development.

All YMC products are available worldwide through YMC's network of subsidiaries. This worldwide presence as a full-range chromatography supplier ensures that all YMC products are fully available and fully supported both locally and globally. See: https://www.ymcamerica.com/