Albany, NY -- (SBWIRE) -- 10/21/2015 -- Cytomegalovirus (CMV) retinitis, a viral inflammation of the retina, is caused by a member of the herpes-type viruses group. Typically common among people with weakened immune systems, serious CMV retinitis can occur as a result of bone marrow transplants, AIDS, organ transplants, drugs that suppress the immune system, and chemotherapy. People who are HIV positive are most at risk of being affected by CMV retinitis due to the low CD4 cell count.

Active CMV retinitis market can be treated with the help of anti-infective ophthalmic drugs, anti-CMV drugs, anti-CMV intravenous drug therapy, anti-HIV systemic and retinal detachment through vitrectomy, anti-CMV oral ganciclovir, and anti-CMV intraocular therapeutic treatment, among others.

What Drives the Global CMV Retinitis Market?
According to amfAR, The Foundation for AIDS Research, an estimated 37 million people around the world are living with HIV, with 2.6 million below the age of 15. In 2014 alone, approximately 2 million people were newly infected with HIV, of which 220,000 were below the age of 15. People living with HIV infection are more susceptible to CMV retinitis and the staggering rise in the percentage of this demographic is one of the primary factors driving the global CMV retinitis market.

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Among the key regional markets for CMV retinitis – namely North America, Latin America, Europe, Asia Pacific, and the Middle East and Africa – North America, comprising of Canada and the U.S., leads the global market owing to the presence of a large number of major manufacturers in these countries. Europe is the second largest market for CMV retinitis for the same reason – that leading players situated in European countries conduct most of their operations in the local markets. Latin America and Asia Pacific are proving to be highly lucrative markets for CMV retinitis owing to the rising prevalence of immunodeficiency diseases in these regions.

There are numerous strong players competing in the worldwide market for CMV retinitis: CSL Behring, Mylan N.V., Endo Pharmaceuticals, Inc., Luitpold Pharmaceuticals, Inc., Emcure Pharms, Ltd., Hospira, Inc., Bausch & Lomb Incorporated, F. Hoffmann-La Roche Ltd., and Valeant Pharmaceuticals International, Inc.

Looming Patent Expiry Could be a Threat to Global CMV Retinitis Market
One of the first hurdles that the global CMV retinitis market will be facing is the patent expiry of leading branded products available in the market. Up until 2015, F. Hoffman-La Roche dominated the CMV retinitis market with Valcyte, the patent of which is due to expire in 2015.

Another significant challenge facing the CMV retinitis market is weak competition. The low safety profile of current marketed drugs has rendered the present competitive scenario rather weak. Even with their significantly high efficacy, the treatment options available today are not entirely successful in meeting the demand owing to their low safety profile, especially of drugs in the CMV retinitis induction therapy.

Thanks to improvised HIV infection treatment options, the incidence of CMV retinitis has gone down, leading to a slow growth in patient population. This indicates that in spite of the high percentage of people living with HIV, the market for CMV retinitis is expected to decline.

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