Critical Limb Ischemia (CLI) – Major Players Involved in Therapy Development
Critical Limb Ischemia (CLI) is a severe form of peripheral artery disease (PAD). It occurs with severe obstructions in the arteries which leads to reduced blood flow to the extremities. CLI causative occlusion could be acute or chronic. CLI may progress to severe pain and skin ulcers and is associated with high risk cardiovascular events such as myocardial infarction and mortality. CLI can also be divided into rest pain and tissue loss based on symptoms appears. Rest pain is a...
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