The advent of bio-ceramic technology has lead in revolutionizing endodontic reparative cement material for dental treatment. Endodontic reparative cement is advantageous as they provide good biocompatibility with a high level of osteoconductivity that makes them ideal for endodontic care. Endodontic reparative cement is a bio-ceramic material and variety of them are available in the market such as calcium-enriched mixture (CEM) cement, endosequencer sealer, and root repair materials. Endodontic reparative cement has many additional characteristics such as they take lesser setting time with no staining in tooth, efficient handling, and blocks bacterial leakage. Endodontic reparative cement is widely adopted for dental implants and coating of implants, and timely evolution in them results in an alteration which results in enormous productive changes. Endodontic reparative cement are used in applications such as pulp capping procedure, apexification, apexogenesis, and furcation repair. Variety of bio-ceramics are available, including, alumina and zirconia, bioactive glass, calcium silicates, hydroxyapatite, and many others. Endodontic reparative cement is classified based on characteristics such as bioinert, bioactive, and biodegradable properties. The properties of endodontic reparative cement such as biocompatibility, hermetic seal, formation of strong chemical bonds in tooth's vicinity, excellent radiopacity, osteoconductivity, tissue fluid insolubility, and ease in handling, makes them interesting in dentistry applications. In addition, glass ionomer cement is also used in endodontic applications and used as a temporary restoration material during endodontic therapies. Mineral trioxide aggregate (MTA) is also an endodontic reparative cement and are used in applications such as root-end filling, pulp therapy, perforation repair, and apical barrier formation for teeth.