Varicose vein closure device is a minimally invasive surgical procedure of varicose vein and is based on radiofrequency (electricity) energy to provide heat and seal the targeted blood vessels of legs using an adhesive agent. The affected varicose vein can result in causing mild pain, skin ulcers, blood clots, skin ulcers, or other problems. In accordance with the National Institute of Health (NIH), if these issues are major, healthcare personnel recommends surgical procedures to close or remove affected veins. Varicose vein closure device is adapted for the patients with superficial varicose veins of legs causing particular symptoms. In general, varicose vein closure device is equipped with adhesive (n-butyl-2-cyanoacrylate), the delivery system including dispenser gun, dispenser tips, syringes, catheter, and guidewire. Varicose vein closure device is used as a single system and is different in accordance with different procedures such as in procedures using drugs, radio waves, or laser in the epidermis to seal or remove veins. Varicose vein closure device is widely adopted in varicose veins treatment as it permanently closes the affected vein with an adhesive, offering patients other treatment option for varicose veins symptoms.