New Report Offers Analysis and Insights on Retinoic Acid Receptor Alpha- Pipeline Review - H2 2017
Retinoic Acid Receptor Alpha, a nuclear receptor, is encoded by RARA gene. RARA plays a vital role in spermatogenesis by regulating the development of germ cells induced by retinoic acid. It promotes the development and survival of meiotic prophase spermatocytes in the early stage. Expression of targeted genes is regulated in ligand-dependent manner with the help of recruitment of chromatin complexes encompassing KMT2E/MLL5 and also mediates the granulopoiesis induced by retinoic acid.
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