Sepsis is a serious life threatening illness caused by the host immune system's response to a bacterial infection. Sepsis is among the most common causes of death in hospitals. Sepsis occurs when the immune system of the host responds to an infection, and then chemicals are released by the immune system to treat the infection. Upon entering the blood stream, this causes inflammation throughout the body. It leads to blood clots, leakage in blood vessels and poor blood flow, and it deprives the vital organs of the body of oxygen and nutrients. Sepsis is considered as a three staged syndrome by many physicians starting with sepsis, leading to severe sepsis, and finally septic shock, which is considered as a medical emergency. People with a weak immune system, children, elderly people, and people with chronic diseases such as cancer, AIDS, diabetes, etc. are among high risk of contracting sepsis. The current methods of sepsis diagnostics rely on non-specific physiological and clinical criteria, which many a times makes it difficult to differentiate sepsis, from a systematic inflammatory response caused by normal inflammation. Blood test is the preliminary test for the evidence of infection, clotting, and impaired oxygen availability. Other laboratory tests such as urine, wound secretions and respiratory secretions are followed. If the confirmation of sepsis and the source of inflammation is not found using these tests, then X-rays, Computerized Tomography, Ultrasound, and Magnetic Resonance Imaging (MRI) are used.