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In comparison with major diseases, the targeting of rare diseases poses many different challenges, necessitating consideration of bespoke R&D strategies for drug discovery efforts to be successful. This report examines the issues that need to be considered in the earliest stages of embarking on a rare disease project.

Global Market Direct's pharmaceuticals report, "Rib-X Pharmaceuticals, Inc. - Product Pipeline Review - 2012" provides data on the Rib-X Pharmaceuticals, Inc.'s research and development focus. The report includes information on current developmental pipeline, complete with latest updates, and features on discontinued and dormant projects.

Global Market Direct's pharmaceuticals report, "Kyowa Hakko Kirin Pharma, Inc. - Product Pipeline Review - 2012" provides data on the Kyowa Hakko Kirin Pharma, Inc.'s research and development focus. The report includes information on current developmental pipeline, complete with latest updates, and features on discontinued and dormant projects.

BMI View: For a country keen to wean itself off of fossil fuels, the decision to phase out nuclear energy represents a fresh and unwelcome challenge. Gas consumption seems certain to grow more quickly than expected as demand for power rises - until the energy void can be filled through the expansion of renewable sources. Refining capacity is being scaled back to do disappointing returns, so Germany must reduce its consumption of oil products in order to avoid becoming overly dependent on costly imports.

Overall, consumption of fish and seafood was impacted by the growing demand of convenience over the review period. Consumers looked for fish that was easy to cook and good for health. However, the lack of natural resources, partly driven by a rising consumption of fish and seafood in France resulted in more imports with an impact on retail prices. As a result, the fragile economic climate led consumers to opt for more elaborated products at lower retail prices, hence a total volume decline...

Baby and child-specific products registered a performance in 2011, as marketing and the rising birth rate helped to drive sales. As the landscape became more competitive, producers drove their brands with increased marketing activities. This helped to create awareness and promote the benefits of products. Furthermore, year-on-year growth in the birth rate widened the consumer base and boosted sales.

GlobalData's new report, "Brazil Diabetes Care Devices Market Outlook to 2018- Glucose Monitoring and Insulin Delivery" provides key market data on the Brazil Diabetes Care Devices market. The report provides value (USD million), volume (units) and average price (USD) data for each segment and sub-segment within two market categories - Glucose Monitoring and Insulin Delivery. The report also provides company shares and distribution shares data for each of the aforementioned market categories. The report is supplemented with global corporate-level profiles of the key market participants with information on company financials and pipeline products, wherever available.

GlobalData, the industry analysis specialist, has released its new report, "Healthcare, Regulatory and Reimbursement Landscape - Canada". The report is an essential source of information and an analysis on the healthcare, regulatory, and reimbursement landscape of Canada. The report identifies the key trends in the Canadian healthcare market, and also provides insights on the demographic, regulatory, and reimbursement landscape, as well as the healthcare infrastructure. Most importantly, the report provides valuable insights on the trends and segmentation of the pharmaceutical and medical devices markets. This report was developed using data and information sourced from proprietary databases, secondary research, and in-house analysis by GlobalData's team of industry experts.

"Oil and Gas Exploration and Production (E&P) in Colombia - Market Analysis, Competitive Landscape and Forecasts to 2020" is the latest report from GlobalData, the industry analysis specialist, which analyzes the exploration and production industry in Colombia. The report provides information on key sedimentary basins and key regulatory and fiscal regimes in the country. It also provides information about major exploration blocks in each basin, major discoveries, planned fields, active production fields and major exploration companies involved in each of the main basins. The report also covers the historic and forecast production from the country. The report is built using data and information sourced from proprietary databases, primary and secondary research, and in-house analysis by GlobalData's team of industry experts.

GlobalData's new report, "Belgium Cardiovascular Devices Market Outlook to 2018 - Cardiac Rhythm Management, Interventional Cardiology, Peripheral Vascular Devices, Electrophysiology, Prosthetic Heart Valves and Others" provides key market data on the Belgium Cardiovascular Devices market. The report provides value (USD million), volume (units) and average price (USD) data for each segment and sub-segment within ten market categories - Cardiac Rhythm Management, Interventional Cardiology, Peripheral Vascular Devices, Electrophysiology, Prosthetic Heart Valves, Cardiovascular Surgery, Cardiovascular Monitoring and Diagnostic Devices, External Defibrillators, Cardiac Assist Devices and Cardiovascular Prosthetic Devices. The report also provides company shares and distribution shares data for each of the aforementioned market categories. The report is supplemented with global corporate-level profiles of the key market participants with information on company financials and pipeline products, wherever available.

BMI's Taiwan Defense and Security Report for Q3 2012 examines the country's strategic position in the Asia-Pacific region. It provides an overview of the contemporary geopolitical challenges facing the country, and the challenges it may face in the future. The report examines the trends occurring in Taiwan's current and future defense procurement, and the order of battle across its armed forces. The intention is to provide a clear and concise discussion of these issues. The report's general conclusion is that the re-election of Kuomintang President Ma Ying-jeou in early 2012 has paved the way for the continuation of relatively warm cross-strait relations, giving the island confidence about its security outlook for the next few years at least. However, Ma's promotion of good relations with China has led to accusations that he has been neglectful of national defense. Perhaps to counter this criticism, Taipei has increased its defense budget for 2012 and is now looking to move forwards with some key defense programs, notably submarine and fighter aircraft procurement. However, China's influence also makes it awkward politically for the US to supply Taiwan with advanced weaponry. As a result Taiwan will continue to depend on the US for only some of its security needs, while also having to develop what it can domestically. Over the last quarter BMI has revised the following forecasts/views: ???? An ambitious new project to develop new submarines domestically has already run into difficulty, with the Ministry of National Defense pouring cold water on a proposal by a Taiwanese shipbuilder to entrust it with the submarine program. Lawmakers attacked the MND for failing to support local industry in its attempts to manage the program, but the fact remains that Taiwanese firms lack the expertise needed for the construction of submarines. ???? New complexities have been added to Taiwan's F-16 program, with the US House of Representatives voting in May to sell the island at least 66 new F-16s. The Obama administration had previously refrained from doing this for fear of provoking China. Taiwan was already engaged in negotiations about an upgrade program for its existing F-16 fleet, which lawmakers have criticized as being overpriced. The prospect of new aircraft may now encourage Taiwan to defer a decision regarding the upgrades. ???? The prototype of a new class of missile fast attack craft was commissioned in May, meaning that an important naval program is now ready to begin. Up to 12 stealthy catamarans will be built as part of an US$853mn project. Taiwan Defense & Security Report Q3 2012 © Business Monitor International Ltd Page 6 ???? Supersonic HS-3 anti-ship missiles are starting to be fitted to Taiwanese naval vessels. These represent a powerful new deterrent against Chinese forces.

Oil and Gas Exploration and Production Outlook in US California to 2016 - Production Analysis, Forecasts and Details of Major Crude Oil and Natural Gas Blocks and Fields

South Korea's trade performance took a hit going into the second half of 2012, with the country's freight industry badly positioned as a result. Exports collapsed 8.8% year-on-year (y-o-y) in July while imports saw a slippage of 5.5%, adhering firmly to the broader downward trajectory. Following the consolidation in export activity that began in early 2011, we are now likely to witness a protracted period of contraction in export performance as the global economy continues to weaken going forward. South Korea's main ports of Busan and Ulsan will both be adversely affected by a slump in external demand and, therefore, both will see less throughput this year compared to recent times.

Mark and Julie Saboil, the founders of Hushamok, originally created their baby hammock products to sooth their own newborn, and began offering them to customers in the United States after finding great success in their own home. They are now offering their products to parents around the globe.

Manufacturers benefit in many ways by using Fishbowl’s Manufacturing Option. Fishbowl provides several competitive advantages, including configurable bills of materials, instructions, and stages; tracks tens of thousands of parts and integrates with QuickBooks.

Lift'n Buddy (liftnbuddy.com) is the revolutionary mobile lifting device that combines the best of a standard two-wheeler's durability and functionality, with automatic lifting and lowering capabilities. Lift’n Buddy was the recipient of the 2012 Wall Street Journal Technology Innovation Awards for Technology Design as well as the Edison Award, Lift’n Buddy was recognized for new product innovation, in the category of Industrial Design Tools. The Lift'n Buddy has been designed with proper ergonomics and safety in mind for any person and any moving and lifting job. These mobile lifting devices, fabricated of durable, lightweight, extruded aluminum, help companies avoid the exposure of employee injury, litigation, and workers’ compensation claims.

SCL Insights recently had manufacturing journalist, Thomas R. Cutler contribute a feature article regarding the Food Safety Modernization Act (FSMA)

The statistics for robots within the factory floor have changed dramatically over the past decade, with more than 90% of all robots within factory and assembly lines deployed within the automotive sector; this has changed dramatically with robots entering factories in most industries where there are repetitive tasks which do not require human supervision. Only 50% of the total number of robots deployed, are in use within automotive industries.

TITA’s Director of Operations, John Patton stated, “Our agreement with S.W. Insurance Training Center is the beginning of our commitment to grow schools throughout the state and eventually nationwide. We believe that the classroom teaching model is one that can have sustained growth for years to come.”

As anyone who owns a caravan knows quite well, insuring them can cost a significant amount of money. Although shopping around for the best caravan insurance rates is definitely a good idea, this typically requires making numerous phone calls and visiting various insurance offices in person. This lengthy process often leaves UK caravan owners feeling confused and overwhelmed.

BMI remains cautiously optimistic on the Mexican freight transport sector. While we expect slowing external demand to begin to temper economic growth in Mexico toward the latter half of the year, the country's economic expansion will remain well anchored by fairly solid private consumption and rapid investment growth in the wake of the recent presidential election. This should help support freight transport volume growth. We project growth in all the freight modes we cover in 2012, with road freight the outperformer. This is predicated on consistently strong NAFTA volume growth through the first half of the year. For shipping, the increased involvement of international terminals operators such as APM Terminals underlines the potential of the sector in the years to come.

Maitland Florida chiropractor, Dr. Erik Roach says that chiropractic care does not work. He reveals why his own specialty doesn't work for people.

Mitch Watkins knows a good thing when he sees it. Watkins Distributing Sales and Service adopted the CooLift Delivery system three years ago and has been running its own in-house comparison with 6-wheel carts ever since. "We wanted to speed up delivery, and get more cases delivered with fewer resources, fewer trucks and fewer people, it just speeds up the whole process.” said Watkins

Mark Woeppel, President and CEO of Pinnacle Strategies explained, “RABIT is drawn from the company’s own staff. We help recruit appropriate personnel from across our client’s business. Guided by Pinnacle Strategy consultants, the new team starts to apply highly effective new project management skills. Each day manufacturers see practical, concrete improvements in workflow.”

Mayumi “May” Sappington, founder of the Caviam hair and skin product line and expert in the art of Japanese Hair Straightening, has expanded her product offerings to give her Long Beach and Southern California clients the ultimate hair treatment and care system.