Aseptic meningitis is the inflammation on the protective membrane called ‘meninges’ covering the brain and spinal cord. Aseptic meningitis may be caused by infectious or non-infectious causes. Infectious causes include viral, bacterial, and rarely fungal. 80-90% of aseptic meningitis cases are caused by enteroviruses; but other causes include arboviruses, herpes viruses, measles, mumps, and human immunodeficiency virus. Non-infectious causes include drugs (including non-steroidal anti-inflammatory drugs, trimethoprim/sulfamethoxazole, intravenous immune globulin), sarcoidosis, vasculitis (caused by autoimmune diseases like lupus or Sjogren's syndrome), and malignancy, including metastases to the meninges. Most common symptoms includes fever, body ache, a painful headache, fatigue, and loss of appetite. It can occur at any age but is most common in children under the age of five. People with a weakened immune system caused by organ or bone marrow transplantation, disease, or medication (such as chemotherapy) or suffering from diabetes or AIDs are at enhanced risk of developing aseptic meningitis. The incidence of aseptic meningitis has been reported as 11 per 100,000 population per year. Depending on the type of cause, the male to female ratio may vary. Enteroviruses affects males 1.5 times more than females, while mumps virus affects males 3 times more than females. No specific treatment is available for aseptic meningitis. The patient is managed with supportive therapy. Treatment options may vary depending on specific causes. Most patients with aseptic meningitis completely recover with specific treatment within one to two weeks.